Carter had a little boy with Kem, who died when she miscarried. The ending is left open to interpretation at the moment. Carter was hooked up to what looked like a dialysis machine to me. Others have said it looked like a chemo machine, but I don't think it is. Back in the day, Carter
Lost a kidney when a schizo patient attacked him and Lucy, resulting in Lucy's death. Carter now only has one kidney. So it could mean that he has hepatitis, etc, resulting in dialysis and possibly a need for a kidney transplant. Could be that he has contracted HIV/AIDS. I personally think it's a kidney thing, but I could be way wrong. I do hope they don't plan on killing off Carter, though that would be a good way for them to squeeze in Benton, Lewis, Abby, Ross and Hathaway's return, as in a funeral. I personally would prefer to see the show end with Carter as chief of the ER. To me, that would be a great end to this show.